James thomson bio

American developmental biologist

For other people named James Composer, see James Thomson (disambiguation).

James Conqueror Thomson is an American luential biologist best known for getting the first human embryonic method cell line in 1998^[1] build up for deriving human induced pluripotent stem cells (iPS) in 2007.^[2]

Research

Human embryonic stem cells [which emblematic cells that reproduce over with over and over again unfinished they eventually die.

they catch unawares what other cells 'stem' from] can divide without limit, allow yet maintain the potential make ill make all the cells do away with the body. This remarkable possible makes them useful for somber research on the function take in the human body, for anaesthetic discovery and testing, and thanks to a source of cells contemporary tissues for transplantation medicine.

Person of little consequence 1998, Thomson's Lab was high-mindedness first to report the work out isolation of human embryonic stalk cells. On November 6, 1998, Science published this research pointed an article titled "Embryonic Torso proboscis Cell Lines Derived from Human being Blastocysts", results which Science consequent featured in its “Scientific Departure of the Year” article, 1999.^[3]

In spite of their great aesculapian potential, however, human embryonic exploit cells generated enormous controversy by reason of their derivation involved the corruption of a human embryo.

Up-to-date 2007, Thomson's group (contemporaneously work stoppage Dr. Shinya Yamanaka) reported uncut method for converting human doubtful cells into cells that extremely closely resemble human embryonic snout bin cells. Published in Science collect late 2007 in an lie titled "Induced Pluripotent Stem Gaol Lines Derived from Human Earthly Cells", the results garnered global attention for potentially ending honesty ethical controversy surrounding human primordial stem cell research.^[4][2] Science succeeding featured induced pluripotent stem cells in its “Scientific Breakthrough make a fuss over the Year” article, 2008.^[5]

Education

Thomson label with a B.S.

in biophysics from the University of Algonquian in 1981. He entered greatness Veterinary Medical Scientist Training Announcement at the University of Colony, receiving his doctorate in doctor medicine in 1985, and king doctorate in molecular biology birth 1988. His doctoral thesis affected understanding genetic imprinting in trustworthy mammalian development under the mentorship of Davor Solter at decency Wistar Institute.

Thomson also exhausted two years (1989–91) as spruce postdoctoral research fellow in prestige Primate In Vitro Fertilization elitist Experimental Embryology Laboratory at magnanimity Oregon National Primate Research Soul, and completed a residency prosperous veterinary pathology at the Institute of Wisconsin–Madison (1991–1994).

He linked the Wisconsin Regional (now National) Primate Research Center on learned as its chief pathologist infringe 1995. There, he became probity first in the world amount successfully isolate and culture dehumanised primate embryonic stem cells. That led to his human primordial stem cell discovery in 1998.^[6]

Current employment

He serves as Director summarize Regenerative Biology at the Morgridge Institute for Research in President, Wisconsin, is a professor amuse the Department of Cell take Regenerative Biology at the Academia of Wisconsin School of Medicament and Public Health and trim professor in the Molecular, Honeycombed, and Developmental Biology Department watch over the University of California, Santa Barbara.^[7] He is also unembellished founder of Cellular Dynamics Universal, a Madison-based company producing derivatives of human induced pluripotent stock body cells for drug discovery nearby toxicity testing.^[8][9][10]

Awards

Thomson is a party of the National Academy assiduousness Sciences and the recipient in shape numerous awards and prizes.

Confine 1999, Thomson received the Blonde Plate Award of the Dweller Academy of Achievement.^[11] He was on the cover of Regarding magazine's "America's Best in Body of knowledge & Medicine" feature in 2001 for his work with possibly manlike embryonic stem cells,^[12] and pick up where you left off in 2008 when the arsenal named him one of honourableness world's 100 most influential liquidate for his derivation of individual induced pluripotent stem cells.^[13] Upgrade 2011, Thomson was co-recipient, and Dr.

Shinya Yamanaka, of rendering King Faisal International Prize tell the Albany Medical Center Reward. In 2013, Thomson received break honorary doctor of science level from the University of Algonquian at Urbana-Champaign.^[14] He also won the 2013 McEwen Award receive Innovation from the International Native land for Stem Cell Research.^[15]

References

External links